HONcode

This website is certified by Health On the Net Foundation. Click to verify. This site complies with the HONcode standard for trust worthy health information:
verify here.


Search only trustworthy HONcode health websites:

Affiliations

REACTION is affilliated with these programs and organisations:

REACTION is delivering better and more efficient healthcare services in Europe, thus supporting the Commissions activities in ICT for Health: eHealth.



The REACTION platform allows for the creation of inclusive applications with accessibility for all. The project supports the Commissions campaign: eInclusion - be part of it!



Sign In

Enter Username

Password



Forgotten your password?
Request a new one here.

Facts



The REACTION project is a 4-year project started in 2010. It is partly funded by the European Commission under the 7th Framework Programme in the area of Personal Health Systems under Grant Agreement no. 248590

 Impressum   Privacy

Previous Newsletters


Read previous issues of our newsletter here:

April 2014
August 2013
June 2012
August 2011
April 2011
November 2010

Share this

Bookmark and Share

eHealth at Facebook

Join the discussion on EC eHealth at Facebook!

Downloads: Closed-loop insulin delivery using a physiology-based pharmacokinetic/pharmacodynamic model kernel

Downloads Home > Scientific publications/presentations > Closed-loop insulin delivery using a physiology-based pharmacokinetic/pharmacodynamic model kernel

Closed-loop insulin delivery using a physiology-based pharmacokinetic/pharmacodynamic model kernel


Motivation: Automated Glucose Control (AGC), even after decades of research, has not yet reached a clinical stage (Hovorka,NatRevEndocrinol,2011). Major hurdles are the inter- and intra-individual variability of glucose dynamics, insulin uptake and response and related pharmacological lag-times. The explicit distinction between substance and patient properties within physiology-based pharmacokinetic / pharmacodynamic (PBPK/PD) models allows the use of prior knowledge, e.g. organ volumes, for their individual pre-parameterization (Willmann,Biosilico,2003). Together with added mechanistic detail, the approach holds promise in alleviating remaining challenges in AGC.

Poster presentation for ATTD 2012: Advanced Technologies and Treatments for Diabetes, Barcelona Spain, 8-11 February 2012
Created:
Admin
20. March 2012 09:32
Downloads
Download 1782
Info
License: Free with reference
O/S: pdf

Download:
Download
(279 KB)
Download Stats Downloads: 113
Downloaded: 338433
Most Downloaded: REACTION brochure [ 26508 ]
Most Recent: REACTION brochure [ 26508 ]